Osteoarthritis is a well known disease affecting joints, mainly of the hip, knee and spine. Articular cartilage, the lining tissue at the ends of long bones is mainly affected. The underlying bones, joint capsule and synovial fluid also show changes. Pain, swelling, stiffness, catching are common symptoms. In Indians, knee osteoarthritis is very common and even younger people in their fourth decade have some earlier symptoms. In this article I shall discuss the precursor of...